Protein p27 , belonging to the family of inhibitors of cyclin-dependent kinase called CIP / KIP , is currently the subject of intensive research in the field of cell biology and pathomechanisms of proliferative processes , because it not only controls the cell cycle by regulating the activity of CDK -cyclin complexes , but also participates in the induction apoptosis. P27 regulates the activity of CDK -cyclin holoenzymów in two ways. First, it inhibits the kinase activity of the complexes .

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p21WAF1/CIP1: role in the physiology of cells in malignancies