CD39 ( NTPDaza 1 ) ? ektoenzym , present in the endothelium and blood cells , plays an important role in the regulation of coagulation , inflammation , and angiogenesis. As a result of the hydrolysis occurs CD39 extracellular ATP and ADP , and consequently to modulate the function of the P2 purinergic receptors . Tri- and diphosphate nucleoside cells induce phenomena as diverse as proliferation, differentiation , chemotaxis or release of cytokines .