PI (4,5) P2, a unique lipid cell membrane: a variety of features and a multitude of effector proteins

Phosphatidylinositol -4 ,5- bisphosphate [ PI ( 4,5) P2 ] is a lipid contained primarily in the inner layer of the cell membrane . Lipid controls the activity of the selected channels and membrane pumps , and modulates the activity of multiple proteins podbłonowych , including actin cytoskeletal proteins . The hydrolysis and phosphorylation of PI ( 4,5) P2 generated second-order three relays : IP3 , DAG , and PI ( 3,4,5) P3.

Current knowledge of akwaporynach invertebrates with particular emphasis on insect aquaporins

Aquaporins ( AQP ) are among the most common cell membrane integral proteins present in all living organisms. Not built by the presence of water channels in the plasma membrane phospholipid bilayer greatly increases its permeability to water molecules and in some cases also for other small chemical compounds. All presently identified aquaporins are characterized by the same structure , which is typical for the presence of six transmembrane domains and two conserved motifs in the linings cf.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

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