FIND ARTICLE

PARTICIPATION OF 'NON-MUSCLE' STEM CELLS IN REGENERATION OF SKELETAL MUSCLE

Skeletal muscle tissue is characterized by ability to regenerate in response to injury resulting for example from mechanical trauma, toxin or disease. The key role in this process is played by satellite cells localized in skeletal muscle. However, both under physiological and experimental conditions different types of stem cells originating either from skeletal muscle or other tissues can be also involved in regeneration. This raises the hope for potential use of stem cells in the therapy for skeletal muscles diseases, such as muscular dystrophies or spinal muscle atrophy.

STRUCTURAL, BIOCHEMICAL AND FUCTIONAL CHARACTERISTIC OF THE EXTRAOCULAR MUSCLES

Extraocular muscles are characterized by excellent neuromuscular control (one axon inne- rvates about only 7 muscle fibres) which allowed high precision eye movements and normal, binocular vision. In comparison to skeletal muscles extraocular muscles are characterized by higher maximal shortening velocity and lower maximal isometric force, expressed by amount of force generated per cross sectional surface area unit.

STRUCTURAL, BIOCHEMICAL AND FUCTIONAL CHARACTERISTIC OF THE EXTRAOCULAR MUSCLES

Extraocular muscles are characterized by excellent neuromuscular control (one axon inne- rvates about only 7 muscle fibres) which allowed high precision eye movements and normal, binocular vision. In comparison to skeletal muscles extraocular muscles are characterized by higher maximal shortening velocity and lower maximal isometric force, expressed by amount of force generated per cross sectional surface area unit.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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