FIND ARTICLE

Genetic aspects of human reproduction

The genetic factor is one of the most prominent reasons for the elimination of embryos / fetuses, as well as the so-called. spontaneous abortions. Still many technical difficulties makes keeping so. pre-implantation diagnosis, gamete chromosomal level. Programs extracorporeal fertilization in vitro must be particularly careful supervision surrounded genetic. Raises the danger of increased incidence of genetic defects, depending on the age of the parents.

Auto sperm antigens: II. Application and functional aspects

The main component of the outer surface of the eukaryotic cell membrane Sugar moieties. Their presence determines the physicochemical, immunological and biological properties of the cell membrane. The oligosaccharide residues, as individuals carrying an unusually rich biological information, also play a crucial role in intercellular interactions. In the process of fertilization, the interaction of glycoprotein receptors and their ligands present on the surface of male and female gametes, determining the species-specific recognition and subsequent fertilization stages.

Auto sperm antigens: I. Characteristics Immunobiological

Sperm antigens may provoke iso-and autoimmune diseases. It is therefore important to identify and to isolate sperm autoantigens specifically reacting with the antibodies. This may not only have a learning value, but also be applied to control reproduction. This article describes the known autoantigens sperm present both on the surface and inside the cell. It also presents the results of studies describing attempts to sensitize and utility of laboratory animals to induce infertility.

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The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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