Role of MAP kinase in the immune response

MAP kinases , which include three families : the ERK , JNK and p38 , are intracellular signaling pathways by which signals can be received from the biological response of the receptor and a cell, and their activity determines the proper functioning of the immune system. MAP kinases are involved in the activation of the innate defense mechanisms involved in the cytokine production under the influence of signals from TLR receptors , and effector pathways are at the same time , which enable the cell response to cytokines.

Suppression of apoptosis in virus infections chordopoks

Viruses , including poxvirus , are known to possess efficient mechanisms allowing them to escape from the immune system of the infected host. One such mechanism is the possibility of inducing or suppressive effects of viruses on programmed cell death ( apoptosis ) . In this paper, the characteristics of the different ways of suppression of apoptosis by gene products of some chordopokswirusów ( orthopoxvirus , Leporipoxvirus and molluscipokswirusów ) . For proteins that are involved in the suppression of apoptosis by caspase inhibitors include poxvirus ?

The role of macrophages in the reproductive tract of mammals: from Paul Ehrlich to modern reproductive immunology

Labor in mammals leads to the exit of sterile fetus under normal conditions , to the external environment of the uterus , where the baby is exposed to even a number of dangers associated with its immediate contact with a variety of infectious agents (bacteria , viruses and / or pathogenic fungi ) . The immune system in which macrophages are an important component , the body tries to protect not only against pathogens , but other factors posing a danger to the body.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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