The dynamic development of technical sciences and information technology allows now for acquisition of microscopic images of histological sections, not only using digital cameras, but also through specialized devices called scanners. The images obtained using scanners and stored in a computer storage device are called virtual slides and, together with special software, are known as virtual microscopy. The virtual slides can be analyzed on a computer monitor by panoramic viewing or using a detailed image examination at higher magnification.

The cause of proteinuria in idiopathic nephrotic syndromes in children is increased permeability of the glomerular filtration barrier following the action of immune and non-immune . Podocytes , thanks to specific proteins of the cytoskeleton ( cytokeratin , vimentin , actin ) and particles stabilizing their intracellular organization (complex podokaliksyna - ezryna - On exchanger regulatory factor -H - actin , synaptopodin ) and proteins films fissured ( podocyn , nephrin ) are responsible for the proper filtration process in the glomerulus .