FIND ARTICLE

Volume: 
Issue: 
1
Date of issue: 

Increasing rate of aged people in societies of developed countries is inevitably connected with occurrence of health problems closely related to this period of life. Ageing as well as old age itself, being a stage of life, are associated with coexisting involutional changes in organs, systems of organs, and old age diseases, accompanying this period of life. In physiological ageing process the disorders mainly concern haematopoesis, especially in conditions of so called hematological stress. It influences the limitations in bone marrow compensation abilities concerning quick leveling of peripheral blood deficits in case of increased demand. It can be connected with telomer hypothesis of ageing. Moreover, the quantitative and qualitative changes in stem cell population are influenced by mutually related factors such as: gene mutations, oxidative stress, uncontrollable apoptosis, regulative disorders of cyto- kine production. Ageing may also influence the structural changes of erythrocytary membranes, intensi- fication of catabolic processes, and decreased erythropoietin production in kidneys.In aged people, the listed factors are conductive to develop anemies of various etiology. These frequent haematopoietic system diseases, significantly increasing morbidity and mortality in this age group, often result in cardio- vascular system diseases, cognitive functions disorders, functional disorders, and fall-downs. They nega- tively influence the quality of life, however the diagnosis and therapy of old age anemia is a complex geriatric problem.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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