FIND ARTICLE

Volume: 
Supplement: 
20
Date of issue: 

Many cases of male infertility are genetic and molecular leading to morphological and functional abnormalities of sperm. Development and use of assisted reproductive techniques, especially Intracytoplasmic Sperm Injection (ICSI? Polish no date), creates the risk of introducing an egg cell with abnormal sperm DNA (eg, impaired condensation and cuts). This can cause a lack of concept or early miscarriage. The article describes two tests (Sperm Chromatin Structure Assay and TUNEL), involving the use of flow cytometry for the early detection of disorders condensation and DNA integrity in a large number of sperm. These tests are important prognostic for fertilization in vivo and in vitro.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

PBK Postępby biologi komórki