FIND ARTICLE

Volume: 
Issue: 
3
Date of issue: 

Blood cells are exposed to any agent absorbed or injected into the bloodstream, even those rapidly metabolised and extracted. Although anucleated, blood platelets are highly organized cells, rich in different types of organelles. They respond to small amounts of circulating molecules by secreting a number of active compounds stored in specific granules. That«s the reason blood platelets are used as pharmacological model for new drugs evaluation for many years. The use of platelets as models has not only been confined to coagulation assay but also has extended to other cell types like: neuronal cells and vascular smooth muscle cells. This review presents the main information about structure of blood platelets, their activation, methods for monitoring of their function and using platelets as pharmacolo- gical model.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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