FIND ARTICLE

Volume: 
Issue: 
4
Date of issue: 

Cerebellin is a relatively new and little-known neuropeptide, built of 16 amino acids. It is now known about the existence of four precursor proteins termed precerebeliny. Within a single species for each precerebellins genes located on different chromosomes, but in each case consist of three exons. Comparison between precerebellins between different species reveals their very high homology. With the presence of immunoreactive cerebellin RIA demonstrated, inter alia, in the cerebellum and other areas of the brain, gastrointestinal tract, kidney, adrenal glands and in the normal and their tumors. Cerebellin action is not fully understood. This peptide promotes, among other things, and aldosterone secretion of cortisol / corticosterone from the adrenal cortex, moreover, directly stimulates the release of catecholamines from the adrenal medulla. It is suggested that the inhibitory effect on thyroid function cerebellin.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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