FIND ARTICLE

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1
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The result of the work of many research teams was to establish significant correlations between specific cytogenetic abnormalities and histological type of human malignant lymphomas . Specific karyotypic changes are correlated with characteristic morphology , immunophenotype and set specific clinical features of the tumor. Specific markers of classical cytogenetic methods has been detected karyotype test (lanes G) and fluorescence in situ hybridization (FISH) . Typical cytogenetic aberrations such as translocations : t ( 8 , 14 ) ( q24 , q32 ) in Burkitt's lymphoma (BL) , t (14; 18) ( q32 , q11 ) in follicular lymphoma (FL ) or the t ( 11; 14 ) ( q13 , q32 ) in mantle cell lymphoma ( MCL ) may be useful to define a specific subtype NHL , which has a significant influence on the strategy of treating a patient . Currently, the utility of cytogenetic analysis increases. In certain cases, knowledge of the aberrations kariotypowych allows , in addition to more precise determination of the diagnosis, for predicting response to treatment or disease

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The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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