FIND ARTICLE

Volume: 
Issue: 
3
Date of issue: 

During the last two decades treatment based on selective stimulation of immune system has became a promising anti-neoplastic strategy, testing in several clinical centers all over the world. Vac- cination with dendritic cells previously exposed to tumor antigens seems to be one of the most attrac- tive approaches of immunotherapy. Dendritic cell-based vaccines were tested in many early phase clinical trials in patients with solid tumors, including malignant melanoma. There are also several reports on effectiveness of this therapeutic approach in patients with hematological malignancies, espe- cially malignant lymphomas and multiple myeloma. In this review we summarize theoretical rationale and the ways of preparation of dendritic cell vaccines as well as results of their use in clinical trials with different types of malignancy.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

PBK Postępby biologi komórki