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The article presents the mechanism of action of estrogen and their importance for the proper reproduction male. In the male gonad , estrogens are produced by the Leydig cells and Sertoli and through successive stages gametogenicznych cells . Estrogen receptors are expressed in the testis, efferent ductules , epididymis , and prostate . Estrogens affect the male reproductive system indirectly by regulating the secretion of gonadotropins by the pituitary gland , and directly affecting the proliferation, maturation and function of Leydig cells and Sertoli and controlling division , differentiation, and survival of germ cells . Recent studies conducted in transgenic mice lacking estrogen receptor and aromatase provide conclusive evidence that estrogens and their receptors are necessary for the proper conduct of spermatogenesis and male fertility . Despite numerous studies conducted in animal models , cell cultures , and observation of patients with impaired synthesis of estrogen , many aspects of these hormones on male reproductive function still requires explanation.
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The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

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Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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