FIND ARTICLE

Volume: 
Issue: 
3
Date of issue: 

Follicular dendritic cells (follicular dendritic cells, FDC) are distinct antigen-presenting cells, and are different from the dendritic cells of myeloid origin, function and the presence of different surface markers. FDC occur within the zone B cell follicles of secondary lymphoid organs and play a very important role in the development of germinal centers have the ability to capture antigen-antibody complexes, which for a long time (months or even years) may remain on the surface. FDC cytoplasmic protrusions form a dense network of intertwining B-lymphocytes Direct contact between FDC and B cells is an indispensable in the process of somatic mutation, affinity maturation, class switching and development of memory B cells.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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