FIND ARTICLE

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1
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The aim of the study was to characterize the leukocytes (L) from the peripheral blood of centenarians.The study involved 39 subjects aged 100 years and older (group S – 33 females and 6 males) as well as 40 young healthy individuals aged 20–30 years (group K – 35 females and 5 males). In all of them, the quantitative and qualitative analysis of L from blood smear was performed. Additio- nally, in centenarians, the relationship between the diameter of L and selected serum parameters was studied (vitamin B12, folic acid, iron, C-reactive protein).The mean WBC count as well as mean neutro- phils (N) count and limphocytes (L) count were lower in group S than in group K (p<0.05). Oppositely, the mean monocytes (M) count was higher in group S (p<0.001). The diameter of all analyzed L (N, L, M) in group S was higher in comparison to group K (p<0.0001). There was no relationship between the diameter of analyzed leukocytes and the levels of studied biochemical serum parameters. In conclusion, in centenarians the quantitative and qualitative alterations in peripheral blood leukocytes were found. Further studies are necessary to explain their pathomechanism.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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