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Acid glycosidases ( EC 3.2.1. ) In the nucleus of mammals found in the lysosomes of somatic cells and organs. The germ cells during spermatogenesis appear in the form of acrosome , a lysosomal be rejected . Occurs sperm maturation in the epididymis . In this process, sperm cell surface glycoproteins may be eliminated or modified by masked proteases, glycosidases , and acid glikozylotrasferazy that are synthesized and secreted primarily by endothelial cells . It is suggested that the acid glycosidase are involved in the binding of the sperm to the zona pellucida glycoproteins egg surface . In ? Role of acid glycosidases in the process of fertilization ? encountered more intriguing puzzles than explaining decisions. Recently, convincing evidence of one of them explaining why acid glucosidase showing optimum activity in the acidic pH range and can function occur in the neutral environment of the reproductive tract . It has been demonstrated that the activity of acid glycosidases in a neutral environment reveals itself to their specific (natural ) substrates , a process that may also be subject to the degree of association / dissociation of the enzyme subunits .
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Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

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