FIND ARTICLE

Volume: 
Issue: 
4
Date of issue: 

Spermatogenesis is a very complex process that involves an array of cellular and biochemical events, collectively culminating in the formation of haploid spermatids from diploid spermatogonia. It is widely accepted that germ cell differentiation requires endocrine regulation by gonadotropins and steroid hormones, a local control through paracrine/autocrine factors, and, importantly, cell-cell interactions via specialized cell junctions. These structures participate in the intercellular communication and coordination of cell metabolism. Moreover, cell junctions are known to mediate stable adhesion throughout spermatogenesis and create a specialized environment necessary for germ cell development and movement. The purpose of this review was to demonstrate the molecular structure of testicular cell junctions and their involvement in the regulation of spermatogenesis. Moreover, we discussed recent findings relating to the role of androgens in the regulation of cell junction dynamics in testis.

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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