FIND ARTICLE

Volume: 
Issue: 
4
Date of issue: 
Satellite cells are mitotically potentially active population , adjacent to the striated muscle fibers . The descendants of activated satellite cells ? myoblasts after a number of divisions undergo mergers of muscle fibers , contributing to their growth or regeneration . Skeletal muscle regeneration can also be assisted in extreme cases, no muscle cells , taking myogenesis , such as bone marrow cells . On the other hand , due to its relatively primitive nature of satellite cells reserve used by the body in the process of hematopoiesis . After genetic modification of myoblasts can be carriers of recombinant genes. Recombinant myoblasts genetically transfer genes providing growth factors and their expression in the muscles of the recipient could improve the productivity of the animals. In addition, there are attempts to use them in the treatment of muscular dystrophy in humans. These procedures , however, still face many problems , such as the inability to isolate a pure population of satellite cells , imperfections conditions of in vitro culture , the relatively low efficiency of transformation of these cells and, finally, their poor survival after reimplantation of the skeletal muscles . Detailed knowledge of the biology of satellite cells should in future help to solve these problems.
Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

PBK Postępby biologi komórki