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NEW MECHANISMS OF NK CELLS ACTIVATION DURING VIRAL INFECTIONS

Natural killer (NK) cells are cytotoxic lymphocytes which constitute a significant element of innate immune responses against tumours and cells infected with viruses or parasites. The function of NK cells is tightly regulated and depends on the balance between activating and inhibitory signals. This review focuses on the latest research showing a high redundancy of mechanisms regulating the activity of NK cells during viral infections and indicating their involvement in the adaptive immune response.

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THE ROLE OF GLYCOPROTEINS IN IMMUNITY

Glycans are structures involved in many immunological processes. They covers the surfaces of all cells and they are added to protein and lipid backbones in the process called glycosylation. These molecules are recognized by variety of receptors presented or secreted by some of immunological system cells. Three the most significant receptors that recognize glycans has been described and these are galectins, C-type lectins and Siglecs.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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