Key process transcription factors osteoblastogenesis

One of the key issues for understanding organogenesis is to understand the mechanisms underlying the differentiation of progenitor cells into specialized cells of various tissues. The development of molecular biology methods including transcriptomics and proteomics allows identification and knowledge of the role of various factors and mechanisms for regulating and / or affecting the genetic level to the process of differentiation, as well as to changes in the functioning of the already phenotypically mature cells.

Gene expression of superoxide dismutase in the state of oxidative stress

This paper describes the structure of the gene superoxide dismutase (SOD) and presents the latest news on their expression, with particular emphasis on mechanisms of regulation of gene expression of MnSOD in the state of oxidative stress.

Transcriptional regulation of adipogenesis

The main role of adipocytes is to store triacylglycerol in periods of energy excess and its reserves at the time of energy shortages. These cells act also secretory synthesize many paracrine and endocrine, among others. leptin. Adipogenesis is a multistep process for converting the primordial germ cells and preadipocytes into mature adipocytes. This process is controlled by several genes, particularly PPAR and C / EBP. The polymorphism of these genes may affect the development of obesity in humans and livestock characteristics of fat.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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