Ageing and diseases connected with ageing currently became very important social problem. Ageing processes can be faster because of accumulation of toxic metabolic products. This substances could be products of non enzymatic glycosylation (glycation). Glycation may there fore play an impor- tant role in ageing and has been implicated in the pathophysiology of a number of diseases, like: Alzheimer disease, arteriosclerosis, diabetes, kidney diseases, blood circulation system diseases and lung diseases.