Stem cells are the body of an adult in biology and medicine

The life span of cells is limited and dying cells are replaced with new ones, differentiated cells derived from stem . Stem cells in the adult organism can be detected markers present in both embryonic stem cells and stem cells in the tissues. Examples of the protein markers are : Oct3 / 4 , CXCR4 , Nanos , CD133 , CD34 . Common features of stem cells include: 1) the ability for self-renewal ( division created after the new stem cells ), 2 ) the ability to differentiate into specialized cells of tissues and organs, 3 ) resistance to stress and radiation toxicity .

Embryonic versus adult stem cells in regenerative therapy of brain

Fulfilling the vision treatment of many incurable diseases by the use of continuously proliferating and differentiating into all tissues of the body of human embryonic stem cells ( HP) has so far not gone beyond the experimental stage preclinical studies . Numerous attempts to apply for the same purposes somatic HP derived from mature tissue yielded only moderate clinical effects . The article presents the basic difficulties which slow down the development of cell therapy .

Jaw Bone Augmentation using autologous bone marrow hematopoietic stem cells and platelets: Fractal Analysis of X-ray

The problem of bone tissue augmentation within the jaws is particularly important in terms IMPLANTOLOGY prosthetic rehabilitation , in the absence of sufficient amount needed for bone fixation of dental implants . In recent years, tissue engineering has been proposed methodology allows for the reconstruction of the vertical and horizontal alveolar and alveolar parts of the jaws.

Studies on the origin of intimal myocytes aortic allograft transplantation in the rat

Untangled the intima is a fundamental change in the pathological remodeling of the vessel wall. Studies using aortic allograft transplantation model suggests that a significant part of the resulting intimal myocytes derived from stem cells derived from the recipient. Experiments are carried out to determine the mechanisms controlling migration of smooth muscle cell precursors to the vessel wall.

Stem cells as a therapeutic tool in neurological disorders

Neurodegenerative diseases are a heterogeneous group of diseases with different clinical pictures and different medium , whose common feature is the dysfunction or loss of particularly vulnerable populations of nerve cells. The presence of a selective loss of nerve cells allows the use of a single therapeutic strategy is to replace losses of new cells , able to take the functions of lost cells. For 20 years now attempt to restore normal function via neural stem cell transplantation in neurodegenerative diseases , in particular Parkinson's disease and Huntington's .

Score human stem cells participate in the regeneration of skeletal muscle? mouse model study

SCID mice ability to accept grafts ksengenicznch, allows the study of human stem cells share tissue regeneration. Regeneration of skeletal muscle is a good model for the study of stem cell involvement in the process. Regeneration of skeletal muscles depends on the presence of satellite cells (muscle precursor cells). Apart from them can participate in the regeneration of stem cells from other tissues. The aim of the project is to investigate what might be involved in the regeneration of stem cells in a xenograft system.

CD34 antigen and CD34-positive cells

KHematopoetyczna stem cell gives rise to many types of blood cells and is one of the better -characterized stem cells in the human body. It is suggested that stem cells derived from bone marrow are capable of giving rise to multiple cell types , including neural cells , skeletal muscle , cardiac muscle , liver cells , intestinal epithelial , skin, lung and kidney . Most positive marker for human hematopoietic stem and progenitor cells is the CD34 antigen . Chemically, it is a sialomucin CD34 ? transmembrane glycoprotein.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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