Our understanding of the precise role of polyamines in various plant developmental and morphogenetic processes has advanced considerably by the ability to manipulate polyamines biosynthe- tic pathways using polyamines biosynthesis inhibitors, polyamines-mutants and by adopting various transgenic strategies. The cDNA for almost every biosynthesis polyamine pathway enzyme has been isolated and cloned. This review summarizes our current understanding of the genetic control of polyami- ne metabolism and their role in plant cell.