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THE ROLE OF TRIM RECEPTORS IN IMMUNITY

Recently, TRIM (tripartite motif-containing) proteins attrackted much attention. These receptors constitute a large family of proteins involved in an innate immunity and in a broad range of biological processes. Their universality is conditioned by their diversity, differences in tissue expression and cell localization. TRIMs have been classified into 9 families C-I to C-IX, and additionally C-X and CXI have been described recently. Numbers of TRIMPs vary in different animal species.

AN IRON UPTAKE BY PARASITIC PROTOZOA: RECEPTORS FOR IRON-BINDING PROTEINS

An effective iron uptake by parasitic protozoa is a determining factor for their survival in host. The available iron source, for which the parasite must compete with the macroorganism, depends on the niche where it resides and its life mode (intracellular or/and extracellular). In the paper an iron acquisition from chelate compounds (transferrin, lactoferrin) in selected protozoan species has been presented. A particular interest has been focused on flagellated protozoon, Trypanosoma brucei.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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