The symplasmic transport of protein and RNAs has emerged as a novel mechanism of cell to cell communication in plant. This movement can occur in selective or a non-selective way between neighbouring cells, tissues or in whole plant. The symplasmic transport is under control both during plant development and in response to environmental conditions. The knowledge about RNAs and proteins that move from cell to cell through plasmodesmata and in the whole plant though phloem is still growing. The transport of mRNA such genes like KN1 or CmNCAP1, has been also described.