Nitric oxide (NO) is a free radical that has been extensively studied as a substance causing air pollution and the product of metabolism of certain groups of bacteria. Ways to download it, metabolism and harmful effects on plants are well established. It turned out , however, that not only the plants respond to changes in the NO concentration in the environment, but they are in a position to produce it .

Nitric oxide (NO) gas is a small molecule with a high reactivity of the resulting radical character. NO in plant cells can be enzymatically synthesized from L -arginine in a reaction catalysed by the enzyme nitric oxide synthase activity or nitrite in a reaction catalyzed by nitrate reductase . It is also possible via non-enzymatic synthesis of NO . The results of the past years have shown a role in the regulation of signal range of physiological processes ranging from seed germination and ending on aging plants .

Disorders of eNOS expression and activity are combined with disease entities such as atherosclerosis , coronary heart disease , hypercholesterolemia and hypertension . The first time was identified eNOS in endothelial cells of veins and arteries ; More detailed studies have shown the presence of this enzyme in myocytes , platelets, and neurons Leydig and Sertoli cells . Endothelial nitric oxide synthase accumulates inwaginacji at specific sites of the cell membrane .

Endothelial nitric oxide synthase ( eNOS ) is one of three enzymes capable of producing nitric oxide ( NO) . This molecule fully key functions in the cardiovascular system . ENOS gene consists of 26 exons and the fragment of chromosome 7 is about the size of 22 kb. Gene promoter does not contain a basic sequence recognized by a complex of RNA polymerase II preinicjacyjny , tzw.TATA box .