Dendritic cells are one of the major populations of immune cells. Due to the presence of specific receptors dendritic cells (DCs) are able to respond to both intra- and extracellular antigens. The diversity of this cell population is a result of differences in localization, stage of maturation, phenotype and function. In recent years there has been a shift in perception of DCs not only as inducers of immune reactivity but also as crucial regulators of immunity, which include ability to induce and maintain tolerance and also as effector cells, which are capable to kill tumor cells (NKDCs).