Katalizujšcymi are enzymes cyclooxygenase metabolism of phospholipids of the cell membrane to the formation of prostanoids ties conducting obejmujšcych prostaglandin and thromboxanes . Prostaglandin kontrolujš variety of physiological processes , such as protection of the gastrointestinal tract, the proper functioning of the kidneys, reproductive processes , and the course of inflammation . It is now known that cyclooxygenase (COX ) is present in at least two isoforms encoded by genes located on different chromosomes .