Score human stem cells participate in the regeneration of skeletal muscle? mouse model study

SCID mice ability to accept grafts ksengenicznch, allows the study of human stem cells share tissue regeneration. Regeneration of skeletal muscle is a good model for the study of stem cell involvement in the process. Regeneration of skeletal muscles depends on the presence of satellite cells (muscle precursor cells). Apart from them can participate in the regeneration of stem cells from other tissues. The aim of the project is to investigate what might be involved in the regeneration of stem cells in a xenograft system.

An attempt isolation of human skeletal muscle stem cells

Our group has demonstrated that early skeletal muscle cells (satellite cells) are expressed on the surface of the CXCR4 receptor. We have also found that isolated from skeletal muscle by successive passages and cells having a cell sorter CXCR4 expression form in vitro in cultured myotubes characteristic. We therefore believe that these cells can be used in the process of regeneration of muscle tissue. Conducted in the present study aims at optimizing the methods of isolation for clinical purposes.

Plasticity not embryonic stem cells: fact or artifact?

Plasticity nieembrionalnych stem cells is one of the most controversial issues of modern biology and experimental medicine . The idea that stem cells can be targeted tissue -differentiate , giving rise to stem cells of other tissues and organs, presents both hope to develop new therapeutic strategies in medicine regeracyjnej just using these cells for treatment , on the other, is an important argument in contributing to the slowdown research into the use of a similar order of embryonic cells .

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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