FIND ARTICLE

Volume: 
Supplement: 
16
Date of issue: 
5 - ns performed molecular dynamics simulation of the hydrated membrane in the liquid crystal phase formed by dimyrystynowej phosphatidylcholine ( DMPC ) and cholesterol ( Chol ) . The aim of the analysis was to clarify the trajectory obtained the mechanism of the ordering and condensing Chol at the atomic level . Ordering of the hydrocarbon chains in the membrane DMPC - Chol is greater than in pure DMPC membrane . Most are arranged adjacent molecular chains of DMPC and Chol smooth surface . In this group the decrease in both the gauche conformation / chain and chain angle with respect to the normal to the film surface . Molecular chains adjacent a rough surface of Chol were less ordered than the surface of the adjacent molecules for the effect of a condensing responsible growth Chol van der Waals interactions between the hydrocarbon chains of DMPC , and not the chains and the interactions between the steroid ring Chol .
Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

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