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Toll-like receptors (TLRs) play a fundamental role in the induction of immune responses. They are richly represented in these places the body, which are a potential gateway infection. The locations of these TLRs, mainly present on antigen presenting cells (APC) and certain non-immune cells, especially epithelial cells, are able to recognize molecular patterns (PAMP) infiltrating the local pathogens and initiate the defensive response. TLRs are therefore an important component of the innate response. When the innate response is not sufficient to eradicate the infection, TLR allow for a smooth transition to the specific response. In addition to inducing an immune response, TLRs are also involved in the regulation processes primarily through effects on regulatory T cells and the effect on Th1/Th2 balance.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

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