TILLING ( Targeting Induced Local called Lesions IN Genomes ) and FOX- hunting ( called Full- length cDNA Over- expressing gene hunting system ) is a new research methods that allow a massive and rapid functional analysis of genes. Acceleration work in this area of the biological sciences is necessary to structure the data obtained in genome sequencing programs , genes and ESTs ( ang.Expressed Sequence Tag) , as well as in research programs of gene expression changes , carried out using a DNA microarray analysis .