FIND ARTICLE

Volume: 
Supplement: 
21
Date of issue: 

The ability of stem cell isolation and in vitro culture in the direction defined Hematopoietic progenitor cells then transplanted patients , creates a chance of a new generation of cell therapy in the treatment of a number of defects of the hematopoietic system , including thrombocytopenia. To date, there have been developed in vitro culture procedures which will provide for the purpose of obtaining a sufficient number of precursors megakariopoezy trials . The aim of the work is to develop the ex vivo expansion of megakaryocyte progenitor cells . The results obtained allowed the initial optimization of culture conditions . Phenotypic characterization confirmed the morphological differentiation of cells grown in the firing direction of megakaryocyte progenitor cells . Correlation of activity ? 1,6- fucosyltransferase ( 6FucT ) with the number of cells with CD41 + phenotype culture indicated that the activity of this enzyme may be a new , another indication różnjcowania and maturation of CD34 + cells towards megakaryocytes .

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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