FIND ARTICLE

Volume: 
Supplement: 
22
Date of issue: 

Mitotic chromosome condensation and segregation are two processes that ensure proper inheritance replicated genome sequence . Although since the publication of the Walther Fleming and published in the first drawings of mitotic cells salamanders have passed more than 120 years , the current state of knowledge still does not allow for the creation of a universal model describing the formation and separation of sister chromatids . Molecular studies indicate that these structures organize involving at least three categories of proteins: ( 1 ) forming the basic components of the interphase chromatin form - core histones and histone H1, ( 2 ) a molecule associated with chromatin in the course of cell cycle , but having different functions in the subsequent stages , such as topoisomerase II , and (3 ) and condensin cohesin complexes , the names of which indicate the involvement of the fusion processes and chromosome condensation . All of these proteins , together with other , not yet known factors involved in the process of forming mitotic chromatin form without changing the basic molecular components present in the interphase nuclei .

Author of the article: 

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

PBK Postępby biologi komórki